When setting up for a game of Sequence, it’s important to first determine how the game will be played based on the number of players. So let’s get started! How to Setup Sequence Game Whether you are new to the game or a seasoned player, you will find something valuable and interesting in this blog. In this blog, we will explain the game rules of Sequence and how to play it. All you need is a Sequence board, a deck of cards, and some chips. It can be played by 2 to 12 players, depending on the version you have. Sequence is a board and card game that combines strategy, luck, and teamwork. If you are looking for a fun and easy game to play with your family or friends, try Sequence.